Historically, alpha-blockers were used as a tool for pharmacologic research to develop a greater understanding of the autonomic nervous system. Using alpha blockers, scientists began characterizing arterial blood pressure and central vasomotor control in the autonomic nervous system. Generally speaking, all of these treatments function by binding an α-blocker to α receptors in the arteries and smooth muscle. Ultimately, this relaxes the smooth muscle or blood vessels, which increases fluid flow in these entities. While there are limited clinical α-blocker uses, in which most α-blockers are used for hypertension or benign prostatic hyperplasia , α-blockers can be used to treat a few other diseases, such as Raynaud's disease, congestive heart failure (CHF), pheochromocytoma, and erectile dysfunction. In patients with this disease, a catecholamine secreting tumor is formed, and causes excess CNS stimulation, such as excess sweating and tachycardia. Nonselective alpha blockers, such as phenoxybenzamine or phentolamine, can be used to mitigate this disease. This drug blocks the activity of epinephrine and norepinephrine by antagonizing the alpha receptors, thus decreasing vascular resistance, increasing vasodilation, and decreasing blood pressure overall. how to taper propranolol Beta blockers, also known as beta antagonists, are a class of drugs that were first developed for the treatment of certain heart conditions and hypertension. Later, beta blockers were also found to be useful in glaucoma, migraine, and some psychiatric disorders such as performance anxiety, tremors secondary to lithium, and movement disorders that are caused by some drugs used in the treatment of psychosis . In the United States, the most commonly used beta blocker used in psychiatric practice is propranolol (Inderal). Nadolol (Corgard), metoprolol (Lopressor), and atenolol (Tenormin) are also used in psychiatric practice but to a lesser degree. Beta blockers are proven effective in the treatment of performance anxiety, lithium-induced tremor, and neuroleptic-induced akathisia (a physical condition caused by certain antipsychotic drugs). Beta blockers have sometimes been used with benzodiazepines in treating alcohol withdrawal. Beta blockers act on that part of the central nervous system that controls mental alertness, lung function, heart rate, and blood vessels. Azithromycin review Order acyclovir online uk WebMD looks at the use of beta-blocker therapy for heart disease. where to buy propecia uk forum In addition, metoprolol is used to treat patients with heart failure. This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain. Toprol XL metoprolol is a beta-blocker prescribed for treating high blood pressure, heart pain, abnormal rhythms of the heart, and some neurologic conditions. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Fatigue is a recognized and common side effect of beta-blockers that can have significant effects on quality of life. Listing a study does not mean it has been evaluated by the U. Worse, many people taking a beta-blocker for years are not even aware of the reduction of energy with which they are living. Beta-blockers are prescribed to millions of people for treatment of hypertension. A new vasodilating beta-blocker, nebivolol, which is approved by the FDA for treatment of hypertension, appears to be far less associated with fatigue than are most currently available beta-blockers. The purpose of this study is to compare nebivolol with the current best-selling beta-blocker, metoprolol, and determine whether there is a significant difference in side effects including fatigue, reduced exertion tolerance, and reduced quality of life. In this study, 30 subjects will take each of the 2 study drugs for 8 weeks, consisting of 4 weeks at a lower dose, and 4 weeks at a higher dose. All dosages are FDA-approved for treatment of hypertension. Beta-blockers are one of the most widely prescribed classes of drugs to treat hypertension (high blood pressure) and are a mainstay treatment of congestive heart failure. Beta-blockers work by blocking the effects of epinephrine (adrenaline) and slowing the heart's rate, thereby decreasing the heart’s demand for oxygen. Long-term use of beta-blockers helps manage chronic heart failure. If you have asthma or COPD, your doctor may not prescribe a beta-blocker because it may make your breathing symptoms worse. If you have heart failure and severe lung congestion, your doctor will treat your congestion before prescribing a beta-blocker. You can take them in the morning, at meals, and at bedtime. When you take them with food, you may have fewer side effects because your body absorbs the drug slower. Metoprolol beta blocker side effects Metoprolol Side Effects, Dosage, Uses, and More - Healthline, Metoprolol Oral Route Side Effects - Mayo Clinic Propecia women reviews Side effects Beta blockers can cause undesired decreases in blood pressure and are typically not given if blood pressure is 90/60 mm Hg or less. Beta blockers - dose, effects, therapy, withdrawal, people, used. Common Side Effects of Toprol XL Metoprolol Succinate Drug. Beta blockers - NHS Why do I need to take a beta-blocker. The amount of medicine that you need to take may vary. Not all of the side effects for beta-blockers are listed here. prednisone back pain Metoprolol, marketed under the tradename Lopressor among others, is a medication of the. Since the FDA does not regulate the practice of medicine after the drug has been approved, it is legal to prescribe beta blockers for other treatments. Hypothesis the beta-blocker nebivolol is associated with less fatigue than metoprolol, the most widely-prescribed beta-blocker; Methods a double-blinded.