It is a disabling and painful condition which can lead to substantial loss of mobility due to pain and joint destruction. I've been off it a few days and thankfully my plumbing is back to normal it seems and the huge acne has stopped/gone. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and... Since I'm a woman I managed to bypass the plumbing problems while on the prednisone (I'm on 30 mg), but you're right, the acne is BAD!! Considering the state my joints are in though, I suppose that's the least of my problems. Is hydroxychloroquine sulfate Alternatives for hydroxychloroquine plaquenil Plaquenil vs methotrexate Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. Mar 24, 2011 I tell ya, these AI diseases are nothing to sneeze at and neither is bad fibromyalgia. I don't know if we get the fibro worse with AI diseases or what but I was in so much pain. The fatigue was horrible too. I am glad I switched to the cymbalta, perhaps the combination of it and 400 mg of plaquenil will work for me. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. My doctor was only able to find it after I requested a MRI of my hands. Of course neither has the prednisone, sulfasalazine, or methotrexate. Hi guys, I was diagnosed with RA in April 08 and I'm 29 years old. I've been on plaquenil for over 4 months and it hasn't done squat for me. How to tell if plaquenil is working Signs That Your Biologic for RA Isn't Working, What next if plaquenil doesn't work? Chloroquine primaquine side effects If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil Side Effects on Your Eyes and Vision. Hydroxychloroquine Plaquenil. Plaquenil Oral Uses, Side Effects, Interactions.. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Study Raises Questions about Sjogren's and Plaquenil. For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system.