These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Affect of hydroxychloroquine Does plaquenil help with inflammation Plaquenil maculopathy photos Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. The amount of hydroxychloroquine excreted in the urine as unchanged drug ranges from 6% to 60% median 23%, and 17% is excreted in the urine as metabolized drug. Twenty-four percent to 25% of hydroxychloroquine is excreted in feces, 5% is sloughed off in skin, and 45% is stored in lean tissues. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Hydroxychloroquine itp Will you have Thrombocytopenia with Plaquenil - eHealthMe, Hydroxychloroquine Information for Providers AIDSinfo Chloroquine cellular toxicitySynthesis procedure of chloroquineHow to stop chloroquine itchingPlaquenil and quinacrine not working anymore for lupus Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine Uses, Dosage & Side Effects -. Plaquenil Uses, Dosage & Side Effects -. Why hydroxychloroquine can treat primary ITP with positive ANA antibody.. Hydroxychloroquine HCQ, an antimalarial drug, is essential treatment for SLE 18. So far, only one study suggested that HCQ could be effective for ITP associated with SLE 19. We report the results of HCQ used to treat ITP in adults with ANA, with or without SLE. Apr 04, 2013 Immune thrombocytopenic purpura ITP is thought to be an autoimmune disorder mediated by autoantibodies with no known etiology, and the incidence is approximately 2.5 per 100,000 persons per year. The goal of treatment is to keep the platelet count above 3×10 4 /mm 3 to prevent major internal organ bleeding. Hydroxychloroquine Plaquenil® is an antimalarial drug with inflammatory properties. Godeau's team 5 conducted a retrospective study between 19 on 40 patients with ITP and positive for antinuclear factors ANF. The results showed the treatment's efficiency 60% response rate and a prolonged immune response.