It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil 200mg side effects Oct findings in plaquenil toxicity Jun 30, 2015 Plaquenil is a prescription medication used to reduce pain and swelling caused by diseases of the immune system such as rheumatoid arthritis, juvenile arthritis, and systemic lupus erythematosus SLE. This medication belongs to a group of drugs called DMARDs disease modifying antirheumatic drugs which work by suppressing the excessive activity of the immune system. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination therapy with other DMARDs for moderate to severe disease. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. What is in plaquenil Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Taking Plaquenil for Rheumatoid Arthritis Does plaquenil cause bile malabsorptionPlaquenil aptt testPlaquenil withdrawal symptoms Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Plaquenil Side Effects on Your Eyes and Vision. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. How Do Ophthalmologists Look for Plaquenil Damage.. According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with arthritis. It can also reduce the incidence of joint damage. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure.