Drugs administered with chloroquine

Discussion in 'Health Canada Drug Database' started by testdriwecs, 03-Mar-2020.

  1. RetChili Moderator

    Drugs administered with chloroquine


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

    Plaquenil vs prednisone Hydroxychloroquine 200mg equivalent Chloroquine phosphate solubility storage Blood clots during period with plaquenil

    To treat malaria Hydroxychloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take this medicine for the full prescribed length of time for malaria. Irreversible retinal damage observed in some patients; significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate, and concurrent macular disease. Popular drugs based on chloroquine phosphate also called nivaquine are Chloroquine FNA, Resochin and Dawaquin. Chloroquine is a 4-aminoquinolone compound with a complicated and still unclear mechanism of action.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Drugs administered with chloroquine

    Chloroquine - FDA prescribing information, side effects and uses, Aralen, Chloroquine phosphate chloroquine dosing.

  2. How long has plaquenil been on the market
  3. Antimalarial plaquenil
  4. Can plaquenil lower your calcium numbers
  5. The drug should be administered with caution to patients having G-6-PD glucose-6 phosphate dehydrogenase deficiency. Auditory Effects In patients with preexisting auditory damage, chloroquine should be administered with caution.

    • Aralen - FDA prescribing information, side effects and uses.
    • Antimalarial medication - Wikipedia.
    • Treating Lupus with Anti-Malarial Drugs Johns Hopkins..

    The drug should be administered with caution to patients having G-6-PD glucose-6 phosphate dehydrogenase deficiency. Auditory Effects In patients with preexisting auditory damage, chloroquine should be administered with caution. In case of any defects in hearing, chloroquine should be immediately discontinued, and Radioactively tagged Chloroquine administered intravenously to pregnant pigmented CBA mice passed rapidly across the placenta and accumulated selectively in the melanin structures of the fetal eyes. It was retained in the ocular tissues for five months after the drug had been eliminated from the rest of the body 2. There are no adequate and well-controlled studies evaluating the safety and efficacy of Chloroquine in pregnant women. Kg or more 1 g chloroquine phosphate 600 mg base orally as an initial dose, followed by 500 mg chloroquine phosphate 300 mg base orally after 6 to 8 hours, then 500 mg chloroquine phosphate 300 mg base orally once a day on the next 2 consecutive days

     
  6. UniT888 User

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine-Resistant Malaria in Travelers Returning from. Malaria Treatment and Prevention - U. S. Pharmacist Chloroquine Resistant Malaria –
     
  7. MVK2 Well-Known Member

    Signs It’s Time to Change Your Rheumatoid Arthritis. Jul 27, 2017 The rheumatoid arthritis treatment that works for you today might not be as effective in the future. Learn signs that it's time to change your treatment plan. Your medication stops working.

    Three Reasons Why Your Thyroid Medication Isn't Working Chris Kresser