One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Downes sm hydroxychloroquine retinopathy Gi problems with hydroxychloroquine Plaquenil to treat mouth disease Methods/design. HERO is an investigator-initiated, multicentre, randomized, double-blind, placebo-controlled trial. A total of 252 subjects with symptomatic hand OA will be recruited across primary and secondary care sites in the UK and randomized on a 11 basis to active treatment or placebo for 12 months. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Macular Society Eye screening for patients taking hydroxychloroquine At this appointment, a number of photographs and scans will be taken of your retina to assess your eye health and your suitability for screening. Not all patients can use the equipment needed for screening, such as people with advanced dementia or Parkinson’s disease. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Hydroxychloroquine eye exam guidance ncbi RCOphth guideline Hydroxychloroquine and Chloroquine., Hydroxychloroquine Plaquenil Toxicity and. Hydroxychloroquine drugbankPlaquenil not working Based on new data, the authors have revised the Academy’s 2011 guidelines to make screening recommendations more concise and practical. Ophthalmologists play a vital role in educating both patients and prescribing physicians about the risk of toxicity associated with exposure to hydroxychloroquine HCQ and chloroquine CQ drugs. Revised guidance for patients exposed to chloroquine.. Eye screening for patients taking hydroxychloroquine.. Ocular side effects of anti-rheumatic medications what a.. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Sir, We agreed with the conclusions of Latasiewicz et al 1 ‘Hydroxychloroquine retinopathy an emerging problem’, which cited cases of hydroxychloroquine HCQ-induced retinal damage. Three patients had received 400 mg HCQ daily for over 15 years equaling 4.93 mg/kg/day in two and 5.6 mg/kg/day in one and all developed maculopathies of varying severity. To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I.