Allergy to plaquenil after being on it for years

Discussion in 'Chloroquine Phosphate' started by Xaret, 16-Mar-2020.

  1. adalthost Guest

    Allergy to plaquenil after being on it for years


    I have been getting these horrible rashes and they are not related to sun exposure. I am starting to wonder if they are related to Plaquenil.

    Plaquenil 2 mg Plaquenil prednisone and methotrexate Hydroxychloroquine normal dose

    You are in a tough situation. If I understand your history correctly, you started having the alopecia despite being on the plaquenil 2 years ago. Now that you're off the plaquenil, there is more fatigue and joint aches. Plaquenil is very effective for the symptoms of achiness and fatigue. However, there might be a price to pay in terms of retinal toxicity especially after taking it for as long as you have. I am interested to see if anyone here has gotten a rash from Plaquenil after being on it for several months. I have been getting these horrible rashes and they are not related to sun exposure. I am starting to wonder if they are related to Plaquenil. My doctor now wants me to start on Chloroquine instead of plaquenil. It seems that after being on a medication for years that has worked seems to loss it's affect or you may develop an allergy to that medication. I had to switch to Cybalta to treat my depression and admit that I was suffering from Fibromyalgia and that Cybalta would would help.

    I've always been one to go for the natural route and am starting to feel like I should just stop taking everything and see what happens - so frustrating. My doctor now wants me to start on Chloroquine instead of plaquenil.

    Allergy to plaquenil after being on it for years

    The Risk of Retinal Toxicity with Plaquenil, Plaqunil rash -

  2. Plaquenil risk of death
  3. Side effects of long term use of hydroxychloroquine
  4. I have a sulfa allergy, and have taken Plaquenil for 4 years without any adverse effects. I can say, however, that I have not had any cross allergic reaction to other drugs sometimes associated with sulfa allergies.

    • Plaquenil and Sulfa Allergies" Lupus Community - Support Group.
    • Doc just put me on a med called Hydr. - HealthUnlocked.
    • Allergy to Plaquenil - Lupus - Inspire.

    Been on Plaquenil for 30 years for rheumatoid arthritis. I don’t know if I have side effect from this drug as they are intermittent. Itching - weird times not consistent Eye watering - constant Headaches - hormonal, RA related Always had thin hair - never fell out No stomach issues ever Get eyes checked 1x a year. Mar 07, 2012 Hi looloo. I hope your able to respond to my question seeing that this discussion took place quit some time ago. Did you feel tingling and numbness when you stopped plaquenil? I am getting off the drug after being on it for four years and I am not experiencing nerve pain in my feet and legs. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use.

     
  5. DeeKay Well-Known Member

    Dosing schedules not well established in children Case reports describe dosage regimens that are effective yet tolerated, such as 12.5 mg PO twice weekly over 2 yr in a child aged 4-6 yr, and 100 mg PO twice weekly over 5 months in a child aged 12 yr; mg/kg dosing not reported Hypersensitivity to chloroquine, 4-aminoquinolones Psoriasis, porphyria, retinal or visual field changes For prevention, may use proguanil concomitantly Shown to cause severe hypoglycemia including loss of consciousness that could be life-threatening in patients treated with or without antidiabetic medications; patients should be warned about risk of hypoglycemia and associated clinical signs and symptoms; patients presenting with clinical symptoms suggestive of hypoglycemia during treatment with chloroquine should have blood glucose level checked and treatment reviewed as necessary Not effective in most areas; CDC recommends mefloquine or atovaquone/proguanil - check CDC traveler information for specific recommendations for region May cause hemolysis in glucose-6 phosphate dehydrogenase (G-6-PD) deficiency; blood monitoring may be needed as hemolytic anemia may occur, in particular in association with other drugs that cause hemolysis Monitor CBC periodically with prolonged therapy Caution with history of auditory damage Caution with hepatic disease, alcoholism, and coadministration with other hepatotoxic drugs May provoke seizures in patients with history of epilepsy Antacids and kaolin reduce chloroquine absorption; separate administration by at least 4 hr Irreversible retinal damage observed in some patients; significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate, and concurrent macular disease A baseline ophthalmological examination should be performed within the first year of initiating therapy; for individuals with significant risk factors, monitoring should include annual examinations; discontinue if ocular toxicity is suspected; patient should be closely observed given that retinal changes (and visual disturbances) may progress even after cessation of therapy In individuals of Asian descent, retinal toxicity may first be noticed outside macula; it is recommended that visual field testing be performed in visual field of central 24 degrees instead of central 10 degrees May exacerbate heart failure Not effective against chloroquine- or hydroxychloroquine-resistant strains of Plasmodium species; information regarding geographic areas where resistance to chloroquine occurs, is available at the Centers for Disease Control and Prevention (gov/malaria) Does not treat hypnozoite liver stage forms of Plasmodium and will therefore not prevent relapses of malaria due to P. ovale; additional treatment with an anti-malarial agent active against these forms, such as an 8-aminoquinoline, is required for the treatment of infections with P. ovale Cases of cardiomyopathy resulting in cardiac failure, in some cases with fatal outcome, reported during long term therapy at high doses; monitor for signs and symptoms of cardiomyopathy and discontinue chloroquine if cardiomyopathy develops; chronic toxicity should be considered when conduction disorders (bundle branch block / atrio-ventricular heart block) diagnosed; if cardiotoxicity suspected, prompt therapy discontinuation may prevent life-threatening complications QT interval prolongation, torsades de pointes, and ventricular arrhythmias reported; risk is greater if chloroquine is administered at high doses; fatal cases reported; use with caution in patients with cardiac disease, a history of ventricular arrhythmias, uncorrected hypokalemia and/or hypomagnesemia, or bradycardia ( There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women; usage during pregnancy should be avoided except in prophylaxis or treatment of malaria when benefit outweighs potential risk to fetus Because of the potential for serious adverse reactions in nursing infants from chloroquine, a decision should be made whether to discontinue nursing or to discontinue drug, taking into account potential clinical benefit of drug to mother A: Generally acceptable. Individual plans may vary and formulary information changes. ARALEN CHLOROQUINE PHOSPHATE, USP Label Malaria Treatment and Prevention Everyday Health Plaquenil vs. Aralen Prescription Treatment for Malaria.
     
  6. kkwindy Moderator

    Methotrexate is an immunosuppressant and chemotherapy drug used to treat a variety of conditions. Lichen planopilaris Genetic and Rare Diseases. Plaquenil Hydroxychloroquine anyone? - Alopecia World Alopecia Areata - Medical Clinical Policy Bulletins Aetna
     
  7. dezender User

    Plaquenil Side Effects on Your Eyes and Vision If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage.

    Taking Plaquenil for Rheumatoid Arthritis
     
  8. T-Jay123 Guest

    What People With Lupus Need To Know About Osteoporosis. Supplements can help ensure that you get adequate amounts of calcium each day, especially in people with a proven milk allergy. The Institute of Medicine recommends a daily calcium intake of 1,000 mg milligrams for men and women up to age 50. Women over age 50 and men over age 70 should increase their intake to 1,200 mg daily.

    Liquid Calcium Citrate 1000mg with D3 16 fl oz Liquid.