Hydroxychloroquine and kidney function

Discussion in 'Chloroquine Phosphate 500 Mg' started by kioit, 27-Feb-2020.

  1. nerevarthelord Well-Known Member

    Hydroxychloroquine and kidney function


    It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc.

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    Here we report on the utility of blood hydroxychloroquine levels in clinical practice, their relationship to disease activity and other variables such as body mass index, height, renal function and ethnicity and the effect of measurement and counseling on subsequent blood levels. Some of her info I would have to question. I have systemic lupus and I see the top rheumatologist in the country and he prescribes hydroxychloroquine Plaquenil for his lupus patients. This is pretty much a miracle drug for lupus patients. It helps with all the joint pains, fevers, keeps cholesterol down, and prevents kidney damage. I have Lupus Nephritis and have had it for almost 12 years now. I strongly suggest you get tested for it because it sounds like that's what you may have, especially with protein in your urine. Better to be safe than sorry. I also take Plaquenil but it's stictly for my joints, all of my other medications are for my kidney function.

    The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea.

    Hydroxychloroquine and kidney function

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  4. This may cause protein to leak into the urine, along with red blood cells. Sometimes a kidney biopsy is needed to establish the exact diagnosis and treatment. Treatment options may include corticosteroids and immunosuppressive drugs to prevent loss of kidney function. This information was first printed in The Moisture Seekers, SSF's patient

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    Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydroxychloroquine in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving this medicine. Breastfeeding Hydroxychloroquine is a derivative of chloroquine that has both antimalarial and antiinflammatory activities and is now most often used as an antirheumatologic agent in systemic lupus erythematosis and rheumatoid arthritis. Hydroxychloroquine therapy has not been associated with liver function abnormalities and is an extremely rare cause of clinically apparent acute liver injury. HRs 1 indicate a shorter time-to-the event renal damage while values 1 indicate a longer time. Kaplan-Meier survival curves as a function of hydroxychloroquine intake and WHO Class IV glomerulonephritis were also examined with renal-damage being the end-point.

     
  5. REDO New Member

    Was told by the doctor that the med, should help me control the systemic arthrirts(Sjogren syndrome /lupus) after 4-6 months of using the med. I am on plaquenil but also experience some of the same things you do. Polymyalgia Rheumatica Plaquenil hydroxychloroquine Withdrawal Pain A randomized study of the effect of withdrawing hydroxychloroquine. Plaquenil Withdrawal – Life As An Anomaly
     
  6. Jana XenForo Moderator

    Mechanisms of drug action and resistance Chloroquine resistance is associated with a decrease in the amount of chloroquine that accumulates in the food vacuole, the site of action for chloroquine. The mechanism for this decreased accumulation is controversial. Some studies have shown that the decrease in drug accumulation is due to an increase in drug efflux.

    Autophagy inhibitor chloroquine induces apoptosis of.
     
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    Cervical Cancer Symptoms, Causes, Stages, and Survival Rates However, since not all people who are infected with HPV will develop cancer, it is likely that other factors also play a role in the development of cervical cancer. Certain risk factors have been identified that increase a woman's risk for developing cervical cancer Tobacco smoking; HIV infection; Immune system suppression

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