Chloroquin quinine

Discussion in 'Canadian Pharmaceuticals Online' started by Red_Devil, 10-Mar-2020.

  1. plat0v Well-Known Member

    Chloroquin quinine


    Chloroquine might be getting new life as an antiviral treatment for the novel coronavirus that emerged in Wuhan, China in late 2019 and has infected some 25,000 people in more than 25 countries. For decades, the drug was a front-line treatment and prophylactic for malaria.

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    After World War II, however, it was largely supplanted by synthetic drugs such as chloroquine that were safer, more effective, and easier to make. Though quinine kills malarial parasites in red blood cells and alleviates fever, it doesn’t completely destroy malaria in the body, allowing relapses to occur if quinine therapy is halted. Is that quinine is pharmaceutical drug a bitter colourless powder, an alkaloid derived from cinchona bark, used to treat malaria and as an ingredient of tonic water while chloroquine is a 4-aminoquinoline drug used to treat and prevent malaria, having the chemical formula c 18 h 26 cln 3. Chloroquine is a synthetic form of quinine, a compound found in the bark of cinchona trees native to Peru and used for centuries to treat malaria. Chloroquine was an essential element of mass drug administration campaigns to combat malaria throughout the second half of the 20th century, and remains one of the World Health Organization’s essential medicines.

    Their drug screen evaluated five other drugs that were not effective. Though the paper is brief, John Lednicky, a professor at the University of Florida’s Emerging Pathogens Institute, found its results intriguing. In a three-page paper published Tuesday in Cell Research, scientists at the Wuhan Institute of Virology’s State Key Laboratory of Virology write that both chloroquine and the antiviral remdesivir were, individually, “highly effective” at inhibiting replication of the novel coronavirus in cell culture.

    Chloroquin quinine

    Chloroquine C18H26ClN3 - PubChem, Quinine vs Chloroquine - What's the difference? WikiDiff

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  3. But then I also remembered that chloroquine is related to quinine, an ingredient in tonic water. I was wondering if it might also make sense to stock up on a whole load of tonic water. However, the only sources I can find mentioning chloroquine as a potential treatment is where its given in combination with remdesivir.

    • Quinine tonic water - use in treating Covid? Coronavirus.
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    In quinine and chloroquine poisoning, severe cardiovascular toxicity results from their Na +-channel blocking effects with hypotension, shock, dysrhythmias and cardiac arrest. Other features include coma, convulsions and, in quinine poisoning, oculotoxicity. Severity of symptoms is closely related to the dose ingested and plasma/serum. Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your. Uses of Chloroquine It is used to treat or prevent malaria. It is used to treat a type of bowel infection. It may be given to you for other reasons.

     
  4. pavely XenForo Moderator

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. What can Hydroxychloroquine Plaquenil do to my eyes? Eye screening for patients taking hydroxychloroquine Plaquenil Hydroxychloroquine toxicity Eye News
     
  5. chubrik New Member

    Immune & Autoimmune - Lupus Plaquenil not working anymore Re Plaquenil not working anymore. I too, started out on 400mg a day. One at breakfast and one at dinner time. Three and a half years later, I am still on 400mg a day. It took a good 4 months for me to feel any benefits from it, but when it kicked in I felt so much better.

    Hydroxychloroquine Side Effects, Dosage, Uses, and More
     
  6. van99 New Member

    Chloroquine Oral Route Proper Use - Mayo Clinic For oral dosage form tablets For prevention of malaria Adults—500 milligrams mg once a week on the same day of each week starting 2 weeks before traveling to an area where malaria occurs, and continued for 8 weeks after leaving the area. Children—Dose is based on body weight and must be determined by your doctor.

    What Are Malaria Pills? Do They Prevent and Treat Malaria?