Is there anyone who take plequenil and suffers from neuropathy? I take plequenil for a week and it seems like it make my neuropathy so bad and I read that plequenil can cause neuropathy. I had neuropathy caused by a side effect from Cyclosporine when taken two years ago. Plaquenil ophthalmic side effects Plaquenil alternatives lupus But, when you're living with lupus, numbness or tingling in your hands or feet may not be minor, passing symptoms. They can signal a condition called peripheral neuropathy, or nerve damage. Lupus is an autoimmune condition that causes the immune system to attack normal, healthy cells and tissue. The drug may be used to treat a type of blood disease called porphyria cutanea tarda, although it's only used in certain cases because it can worsen symptoms. Plaquenil is in a class of medicines known as antimalarials. It's a less toxic version of the older antimalarials, including quinine and chloroquine. Often plaquenil side effects do go away after a few weeks if you persist with the drug. Plaquenil is the only drug i have EVER had side effects to. I lost my appetite, had slightly blurred vision, had worsening peripheral neuropathy, felt nervous and anxious. I was ready to.took a good three weeks. Is there any possibility of this medication also causing neuropathy? I am now on Plaquinel and am beginning to feel some pain in my feet. Can plaquenil worsen neuropathy Irritability and increased hot flashes with Plaquenil, Plaquenil Hydroxychloroquine - Side Effects, Dosage. What happens when yoou stop taking hydroxychloroquine abruptlyWhat should a nurse monitor when taking hydroxychloroquine While gathering this information, seven key questions are asked Table 459-1, the answers to which can usually identify the category of pathology that is present Table 459-2. Despite an extensive evaluation, in approximately half of patients, no etiology is ever found; these patients typically have a predominately sensory polyneuropathy and have been labeled as having idiopathic or cryptogenic sensory polyneuropathy CSPN. Peripheral Neuropathy Harrison's Principles of Internal.. Can Plaquenil cause Peripheral Neuropathy?. Plequenil and neuropathy Sjogren's Syndrome Forums Patient. There are even cases where patients have such acute cases of peripheral neuropathy that they don’t notice open sores or cuts on their feet. The havoc that improper blood sugar wreaks on the body is quite strong. Many people suffering from peripheral neuropathy have an inability to sweat properly. I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. All my issues were resolved over a years time on low doses. Plaquenil and small fiber neuropathy - NeuroTalk Support Groups Learn about how bad can peripheral neuropathy can get here. If we talk about the worst case scenario for when neuropathy gets worse, then there’s a possibility that you might lose feeling in your hands and feet completely, leading to paralysis.