I am currently taking 200mg one time a day and my appetite has seriously decreased in the last two weeks. Just curious if anyone else had this as a side effect. Yes, Plaquenil causes both weight loss and loss of appetite. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. I was not losing weight or have a lack of appetite prior to Plaquenil so it must be the medicine. I personally had terrible nausea for almost 2 years when I was put on plaquinel, the nausea was the first symptom to leave....causing me to gain weight. I just find Im not as hungry as I was before, or that my appetite has changed. Plaquenil and coq10 Homocysteine plaquenil Plaquenil side effects can you drink alcohol Plaquenil caused a loss of appitite and weight loss for me. Both times I started taking it, the first time it was so serious I had to stop taking it. Started again several years later when I flared again and had loss of appitite and weight loss but a bit more moderate. Plaquenil and Weight loss - from FDA reports Summary Weight loss is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. Weight Loss; Full Drug Information. In this case, the cause of loss f appetite and weight loss has to be found. I was just curious if the medication was what caused my appetite to change or what. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. At my last visit my Dr asked me if it had deminished my appetite so she is aware of it and the amount of weight I lost and is not concerned at this moment. I know diarhea is a common side affect of plaquinel. It wasn't that I was eating a lot, it was just that I was actually eating. I was on Prednisone for two months prior to Plaquenil and gained 18 lbs, so I needed to lose the weight anyway. Does plaquenil cause weight gain or weight loss Medications That Can Cause Weight Gain. - Prevention, Will you have Weight loss with Plaquenil - eHealthMe Sigma chloroquine diphosphatase Aug 01, 2009 Lucy, meds effect us all differently. Almost any med that can cause weight loss can also cause weight gain. I also find that eating a lot of carbohydrates helps with the GI effects of the plaq and that can contribute to weight gain. I was on Plaquenil for 2 yrs and gained 60 pounds. Plaquenil and weight gain -. Common and Rare Side Effects for Plaquenil Oral. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Oct 12, 2016 In multivariable models, more weight loss and a greater risk of weight loss odds ratio 1.73 were evident among those receiving leflunomide compared to those receiving methotrexate. Treatment with prednisone was associated with greater weight gain—an average of 0.072 kg/m2. Plaquenil and Weight increased - from FDA reports Summary Weight increased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Actemra, and have Pain. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight.