Hydroxychloroquine and trametinib

Discussion in 'Canada Drugs Online' started by TNVF, 29-Feb-2020.

  1. AlekSv Guest

    Hydroxychloroquine and trametinib


    Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Jan 31, 2019 A Phase I clinical trial to study the side effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer. A Phase I clinical trial to study the side effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer. The primary purpose of this study is to determine the maximum tolerated dose MTD and preliminary safety of hydroxychloroquine HCQ when administered in conjunction with oral dabrafenib and trametinib D+T in patients with advanced BRAF mutant melanoma. This phase I trial studies the sides effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer that has spread to nearby tissue, lymph nodes or other places in the body and cannot be removed by surgery. Trametinib may stop the growth.

    Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria.

    Hydroxychloroquine and trametinib

    Hydroxychloroquine Side Effects, Dosage, Uses, and More, Dabrafenib, Trametinib and Hydroxychloroquine in Patients.

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  6. Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

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    A Phase I clinical trial to study the side effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer. A recent study shows that the combination of MEK inhibitor trametinib and hydroxychloroquine led to a striking disease response in a patient with pancreatic cancer. O'Hara et al. reported the results from a phase II, single arm study in patients with metastatic colon cancer treated with hydroxychloroquine in combination with standard first. When administered in combination with trametinib, take the once-daily dose of trametinib at the same time each day with either the morning dose or the evening dose of TAFINLAR. 2.3 Dose Modifications. For New Primary Cutaneous Malignancies No dose modifications are required.

     
  7. staseg XenForo Moderator

    Applies to chloroquine: oral tablet Along with its needed effects, chloroquine may cause some unwanted effects. Retinal Physician - Hydroxychloroquine Maculopathy An Update. Continuation of long term treatment with hydroxychloroquine. How Is Retinitis Pigmentosa Diagnosed? - VisionAware
     
  8. mrbaz XenForo Moderator

    Treatments for arthritis reduce pain and swelling, slow the progression of disease and minimize permanent damage to joints. Will you have Fatigue with Plaquenil - eHealthMe Plaquenil Indications, Side Effects, Warnings - Plaquenil Side Effects Go Away? DailyStrength
     
  9. Anton Moderator

    Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1.

    Retinal Physician - Hydroxychloroquine Maculopathy An.