I saw a GP about it (not my usual one) and they strongly suspect it is being caused by MTX but I have just spoken to the Rheumy nurse who thinks Hydroxy is the more likely suspect or it may be an autoimmune response so now I have to withhold all rheumy meds. It seems to improve when I am on steroids but only at higher doses. Thanks, Tamara I am on all sorts of meds including MTX and Hydroxy. Plaquenil induced psoriasis Side effects from taking plaquenil I've been on Plaquenil for 6 weeks. I developed a red, raised, welt rash that looked like zebra stripes after being in the sun for 10 minutes. It went away within 30 minutes but then my joints all flared up the next few days. Check with your doctor! And their welt rashes look exactly like the welts I had all over from this reaction. I have never had lupus rash other than the Malar rash on my face and upper chest area, and rash in my scalp. the only way to be sure is to either biopsy the rash or to restart the plaquenil. I wouldn't restart the plaquenil with the rash you have, I would. Plaquenil “. gas, fatigue, diarrhea, some hallucinations, which have subsided as of now, hyper pigmentation, purpura and petechiai med size and small size red pepper dots on skin, have had a rash on abdomen for 3. ” I can't face the GP again, as I am sure I am one of the "heart-sink" patients! I have recently developed an itchy rash which only affects my cheeks and eyebrows and haven't a clue what's causing it, so I hope you get some helpful replies that might help me too! What does a plaquenil rash look like Plaquenil hydroxychloroquine 200mg is it causing itchy skin., Allergic reaction to Plaquenil Lupus Forums at The Lupus. Hydroxychloroquine side effects wikipedia Yes. Hair bleaching, hair loss, skin pigmentation, rash and itching are recognized skin adverse reactions of plaquenil hydroxychloroquine. These reactions tend to be worse if a patient is taking other medications that have similar skin toxicity. Please consult a dermatologist to ensure skin lesions are not psoriatic because Plaquenil hydroxychloroquine use needs special precautions in. Plaquenil hydroxychloroquine 200mg is it causing itchy.. Hydroxychloroquine Sulfate Rash Reports - DrugInformer. Will you have Rashes with Plaquenil - eHealthMe. I broke out with a rash after being on it for a week. I was also on a mild muscle relaxer for about 3 weeks prior to plaquenil. I got off both then started back on plaquenil. No rash so I assumed it was the other med even though I was on it longer and before the plaquenil. Did not resume the other meds. Find information about common, infrequent and rare side effects of Plaquenil Oral. While hydroxychloroquine is considered a relatively safe medication, like all medications there are potential risks. These include body rashes that often will itch. The rash typically occurs in the first 6 weeks and is usually mild. In general, the rash will resolve within 2 weeks after stopping the drug.