When have cancer, you may have a higher risk of blood clots, infection, lymphoedema (swelling) or sun sensitivity. You might need to take extra care when you are travelling. Some people with cancer are more at risk of developing blood clots (deep vein thrombosis or DVT). This is because they have more of the substances and proteins that help the blood to clot. You might also be more at risk if: Sitting for long periods also increases your risk of developing a blood clot. So you need to take care if you’re travelling by car, plane, train or coach. The risk increases on journeys that are over 3 hours. side effect of tamoxifen is blood clots, including deep vein thrombosis (DVT) and pulmonary embolus. In some cases, health care professionals may use the trade name Nolvadex when referring to the generic drug name tamoxifen. This medication is classified as an "anti-estrogen." (For more detail, see "How this drug works" section below). You should seek emergency help and notify your health care provider immediately if you develop sudden chest pain and shortness of breath. Notify your health care provider within 24 hours if you notice that one leg is swollen, red, painful and/or warm to touch and the other is not. A side effect of tamoxifen can be the development of uterine cancer. Women who have not had a hysterectomy should have regular pap smears and gyn examinations. Abnormal vaginal bleeding should be reported to your health care provider.
Kiwikid wrote: Hi I was just wondering if anyone else has developed dvt while on tamoxifen? I'm now on thinners (a daily injection) and am quite concerned about developing pain in my groin (another clot?! I look forward to hearing from anyone who can share their story. Xx kk Sep 28, 2013 PM Moody Moo wrote: I ended up with a DVT in my calf after being on Tamoxifen for about 3 months. Stopped it immediately, went on Lovenox shots for about 2 weeks, and then moved to coumadin for about 4 months. Been off the blood thinners now for about 3 months. In fact, she just vetoed my primary's decision to put me on Depo Provera due to the clot risk, but it's hard to find anything out there that doesn't contain estrogen. Sep 29, 2013 AM kiwikid wrote: Wow Moody I'm on Lupron and tamoxifen and my onc says to continue both! I'm also on lovenox but they say I will stay on it for 6 months as tamoxifen and Coumadin are contraindicated... Thanks for sharing Xx kk Sep 29, 2013 PM Moody Moo wrote: I had unexplained calf pain on one side that I couldn't attribute to muscle strain or anything else for that matter. I knew DVT's were a possible side effect, so I called my MO and she had me go to the ER and get an ultrasound, and it was confirmed that way. Usually in the leg DVT's present with swelling and warmth due to the blood clot limiting circulation. BACKGROUND: In response to findings from the Breast Cancer Prevention Trial that tamoxifen treatment produced a 49% reduction in the risk of invasive breast cancer in a population of women at elevated risk, the National Cancer Institute sponsored a workshop on July 7 and 8, 1998, to develop information to assist in counseling and in weighing the risks and benefits of tamoxifen. Our study was undertaken to develop tools to identify women for whom the benefits outweigh the risks. METHODS: Information was reviewed on the incidence of invasive breast cancer and of lesions, as well as on several other health outcomes, in the absence of tamoxifen treatment. Data on the effects of tamoxifen on these outcomes were also reviewed, and methods were developed to compare the risks and benefits of tamoxifen. RESULTS: The risks and benefits of tamoxifen depend on age and race, as well as on a woman's specific risk factors for breast cancer. In particular, the absolute risks from tamoxifen of endometrial cancer, stroke, pulmonary embolism, and deep vein thrombosis increase with age, and these absolute risks differ between white and black women, as does the protective effect of tamoxifen on fractures. Tables and aids are developed to describe the risks and benefits of tamoxifen and to identify classes of women for whom the benefits outweigh the risks.
A rare, but serious side effect of tamoxifen is blood clots, including deep vein thrombosis DVT and pulmonary embolus. You should seek emergency help and. However, some women who take tamoxifen will still develop breast cancer. effect of tamoxifen on your risk of blood clots, such as deep vein thrombosis DVT.