JAMAJAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Facial Plastic Surgery JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Pollack MHSmoller JW Pharmacologic approaches to treatment-resistant panic disorder. Pollack MHOtto MWRosenbaum JFeds Challenges in Clinical Practice Pharmacologic and Psychosocial Strategies New York, NY Guilford Press1996;89- 112Google Scholar Oehrberg SChristiansen PEBehnke KBorup ALSeverin BSoegaard JCalberg HJudge ROhrstrom JKManniche PM Paroxetine in the treatment of panic disorder: a randomized, double-blind, placebo-controlled study. 1995;167374- 379Google Scholar Den Boer JAWestenberg JGM Effect of a serotonin and noradrenaline uptake inhibitor in panic disorder: a double-blind comparative study with fluvoxamine and maprotiline. 1988;359- 74Google Scholar Sharp DMPower KGSimpson RJSimpson VMoodie EAnstee JAAshford JJ Fluvoxamine, placebo and cognitive behavior therapy used alone and in combination in the treatment of panic disorder and agoraphobia. 1996;10219- 242Google Scholar Reimherr FWByerley WFWard MFLebegue BJWender PH Sertraline, a selective inhibitor of serotonin uptake, for the treatment of outpatients with major depressive disorder. 1988;24200- 205Google Scholar Greist JChouinard GDu Boff EHalaris AKim SWKoran LLiebowitz MLydiard RBRasmussen SWhite KSikes C Double-blind parallel comparison of three dosages of sertraline and placebo in outpatients with obsessive-compulsive disorder. 1995;52289- 295Google Scholar Clark DMSalkovskis PMHackmann AMiddleton HPavlos AGelder M A comparison of cognitive therapy, applied relaxation and imipramine in the treatment of panic disorder. 1994;164759- 769Google Scholar Tesar GERosenbaum JFPollack MHOtto MWSachs GSHerman JBCohen LSSpier SA Double-blind, placebo-controlled comparison of clonazepam and alprazolam for panic disorder. Sertraline is indicated for the treatment of: Major depressive episodes. Prevention of recurrence of major depressive episodes. Obsessive compulsive disorder (OCD) in adults and paediatric patients aged 6-17 years. Post traumatic stress disorder (PTSD) Depression and OCD Sertraline treatment should be started at a dose of 50 mg/day. Panic Disorder, PTSD, and Social Anxiety Disorder Therapy should be initiated at 25 mg/day. After one week, the dose should be increased to 50 mg once daily. This dosage regimen has been shown to reduce the frequency of early treatment emergent side effects characteristic of panic disorder. Depression, OCD, Panic Disorder, Social Anxiety Disorder and PTSD Patients not responding to a 50 mg dose may benefit from dose increases. Dose changes should be made in steps of 50 mg at intervals of at least one week, up to a maximum of 200 mg/day.
Efficacy has been demonstrated in depression, dysthymia, OCD, social anxiety, panic disorder, PTSD, premature ejaculation, and premenstrual dysphoric disorder. It's also sometimes used for eating disorders. The core effect of the substance is that it alters mood. This could mean less anxiety, less depression, a more positive outlook, improved cooperation with others, and greater assertiveness. SSRIs may initially worsen symptoms like depression and anxiety in some people. This changes over a period of weeks, with the efficacy building over time. Some benefits in depression may be noticed in the first 1-2 weeks, but the greatest clinical efficacy arrives in the first couple months. Sertraline oral tablet is a prescription drug that’s available as the brand-name drug Zoloft. This drug may be used as part of a combination therapy. In some cases, they may not be available in every strength or form as the brand-name version. This drug is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. This means you may need to take it with other medications. This drug belongs to a class of drugs called selective serotonin reuptake inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. This drug works by increasing the amount of serotonin, a natural substance in your brain, that helps maintain mental health balance.
Our free Discount Rx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. This site does not dispense medical advice or advice of any kind. Enter your name and email address to receive your free savings card. Site users seeking medical advice about their specific situation should consult with their own physician. Our free Discount Rx savings card can help you and your family save money on your prescriptions. Click In order for us to create your customized Health Savvy programs, we need a little more information about the health topic(s) that you are interested in. This card is accepted at all major chain pharmacies, nationwide. Press "Continue" button below to begin selecting your Health Savvy topic(s). Remember, you need at least one selected topic to use Health Savvy. Enter your name and email address to receive your free savings card. If you choose this option, it cannot be undone, and you'll need to choose at least new topic to continue using your Health Savvy programs. Sertraline has been studied in numerous clinical trials for several conditions. Are you still sure that you want to clear all of you selected topics? After a few weeks of taking sertraline for depression (i would usually take citalopram but the gp said this was no longer being used) i felt on top of the world but after an emotional day at work my ability to cope with my emotions disappeared i became very tearful and quite aggressive towards my husband resulting in me smashing the house up. now this is not me, i'm a quiet depressive and this behaviour shocked and scared me. when i spoke to the doctor she said it was because i drank but ive always enjoyed the odd glass throughout my 20 year history of depressive episodes and never behaved like this and can only put it down to the sertraline. thankfully a different gp listened to me and put me back on citalopram but am keen to know has anyone else experienced this manic and out of control behaviour linked to sertraline?
Studies of sertraline were eligible for inclusion. The dosages used in the included studies, where reported, ranged from 50 to 200 mg/day, and the maximum reported treatment period was 36 weeks. Controlled studies compared sertraline with placebo or with other antidepressants, including fluoxetine, paroxetine and venlafaxine. Sertraline is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors SSRIs. Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Sertraline is used to treat depression, obsessive.