High Dose Oral Furosemide with Salt Ingestion in the Treatment of Refractory Ascites of Liver Cirrhosis. Yakar T, Demir M, Dogan O, Parlakgumus A, Ozer B, Serin E. Clin Invest Med. 2016 Dec 1;39627502. First-line diuretic therapy for cirrhotic ascites is the combined use of spironolactone Aldactone and furosemide Lasix. Beginning dosages are 100mg of.