This medication is used alone or with other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Clonidine belongs to a class of drugs (central alpha agonists) that act in the brain to lower blood pressure. It works by relaxing blood vessels so blood can flow more easily. Take this medication by mouth with or without food as directed by your doctor, usually twice daily (in the morning and at bedtime). If the doses are not equal, take the larger dose at bedtime to decrease the risk of side effects. The dosage is based on your medical condition and response to treatment. The most efficacious treatment for VMS is hormone replacement therapy (HRT) using either estrogen alone or a combination pill of estrogen plus progestin. Women using HRT saw a 75% decrease in weekly hot flashes. With such great results, this has long been used as the therapy of choice for symptomatic perimenopausal women. The Woman’s Health Initiative (WHI) demonstrated some negative effects of these therapies including increased risk of breast cancer as well as various cardiovascular concerns with the combination pill. These adverse effects have made many providers and patients more cautious about using HRT. It is important to note that the WHI was only looking at postmenopausal women using HRT as a preventative therapy, not perimenopausal women and not solely for the treatment of menopause symptoms. For women who prefer not to use HRT or are unable to, there are non-hormonal medications that effectively reduce VMS.
Clo NIDine is a topic covered in the Davis's Drug Guide. To view the entire topic, please sign in or purchase a subscription. Nursing Central is the award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,000 drugs or refer to 65,000 dictionary terms. Explore these free sample topics: Quiring C, Sanoski CA, Vallerand AH. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Drug-Guide/51165/all/clo NIDine. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Drug-Guide/51165/all/clo NIDine TY - ELEC T1 - clo NIDine ID - 51165 A1 - Quiring, Courtney, AU - Sanoski, Cynthia A, AU - Vallerand, April Hazard, BT - Davis's Drug Guide UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Drug-Guide/51165/all/clo NIDine PB - F. Generic Name: Clonidine Hydrochloride Brand Name: Catapres, Catapres-TTS, Dixaril , Duraclon Classifications: cardiovascular agent; central-acting antihypertensive; analgesic Pregnancy Category: C Availability 0.1 mg, 0.2 mg, 0.3 mg tablets; 0.1 mg/24 h, 0.2 mg/24 h; 0.3 mg/24 h transdermal patch; 100 mcg/m L, 500 mcg/m L injection -adrenergic receptors in CNS to inhibit sympathetic vasomotor centers. Central actions reduce plasma concentrations of norepinephrine. It decreases systolic and diastolic BP and heart rate. Orthostatic effects tend to be mild and occur infrequently. Decreases systolic and diastolic BP and heart rate. Orthostatic effects tend to be mild and occur infrequently. Reportedly minimizes or eliminates many of the common clinical S&S associated with withdrawal of heroin, methadone, or other opiates. Route and Dosage Hypertension adult: PO 0.1 mg b.i.d.
Definition and instructions for use of clonidine Catapres, provided by staff members of Cincinnati Children's Hospital Medical Center. Refer to the patient's assessment to determine if he or she is dependent and requires WM. Nurses, who are responsible for monitoring patients in withdrawal. As for management of mild withdrawal, but with the addition of clonidine or.