, commonly referred to as the "Do Not Crush" list, contains medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. Mucous membrane irritation; Note: drug may cause fetal abnormalities; women who are, or may become, pregnant, should not handle capsules; all women should use caution in handling capsules, especially leaking capsules a: Capsule may be opened and the contents taken without chewing or crushing; soft food such as applesauce or pudding may facilitate administration; contents may generally be administered via NG tube using an appropriate fluid provided entire contents are washed down the tube. b: Liquid dosage forms of the product are available; however, dose, frequency of administration, and manufacturers may differ from that of the solid dosage form. c: Antacids and/or milk may prematurely dissolve the coating of the tablet. d: Capsule may be opened and the liquid contents removed for administration. e: The taste of this product in a liquid form would likely be unacceptable to the patient; administration via NG tube should be acceptable. f: Effervescent tablets must be dissolved in the amount of diluent recommended by the manufacturer. Propranolol, which treats high blood pressure, irregular heart rhythms, chest pain, and other heart symptoms, is also approved by the U. Food and Drug Administration (FDA) for preventing migraine attacks. Propranolol falls into the beta-blocker class of medications. Beta blockers reduce the frequency of migraine attacks in 60 to 80 percent of people. It is not clear, however, if propranolol affects active migraine, so it should not be taken to stop migraine attacks already in progress. Propranolol is available in multiple formulations, including tablets, liquid, and a long-acting time-release capsule. Propranolol is the active ingredient in Inderal LA, Inderal XL, and Inno Pran XL. Propranolol works by blocking certain receptors, known as beta receptors, in blood vessels.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you. In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). This medicine should come with a Medication Guide and patient directions. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Remember that this medicine will not cure your high blood pressure, but it does help control it. Inderal LA provides propranolol hydrochloride in a sustained-release capsule for administration once daily. If patients are switched from Inderal Tablets to Inderal LA Capsules, care should be taken to assure that the desired therapeutic effect is maintained. Inderal LA should not be considered a simple mg-for-mg substitute for Inderal. Inderal LA has different kinetics and produces lower blood levels. Retitration may be necessary, especially to maintain effectiveness at the end of the 24-hour dosing interval. The usual initial dosage is 80 mg Inderal LA once daily, whether used alone or added to a diuretic. The dosage may be increased to 120 mg once daily or higher until adequate blood pressure control is achieved.
Propranolol is a beta-blocker used to treat high blood pressure, irregular heartbeats, shaking tremors, and. Dosage Forms and Strengths. Currently, a number of companies make generic propranolol. A long-acting form for once-a-day dosing has also been approved. In 2006, the.